Table 3.
Most frequent adverse events
| Adverse event | Total patients (%) | Grade 1 | Grade 2 | Grade 3 | Grade 4 |
|---|---|---|---|---|---|
| Nausea | 14 (82) | 6 | 7 | 1 | |
| Hyperglycemia | 12 (71) | 8 | 2 | 2 | |
| Neutropenia | 11 (65) | 3 | 6 | 2 | |
| Thrombocytopenia | 11 (65) | 4 | 5 | 1 | 1 |
| Fatigue | 9 (53) | 4 | 2 | 3 | |
| Leukopenia | 9 (53) | 4 | 2 | 3 | |
| Elevated alkaline phosphatase | 6 (35) | 5 | 1 | ||
| Anemia | 6 (35) | 6 | |||
| Anorexia | 6 (35) | 3 | 3 | ||
| AST elevation | 6 (35) | 5 | 1 | ||
| Increased lipase | 6 (35) | 2 | 4 | ||
| Lymphopenia | 6 (35) | 2 | 4 | ||
| Mucositis | 5 (29) | 2 | 2 | 1 | |
| Vomiting | 5 (29) | 1 | 3 | 1 | |
| Hypertriglyeridemia | 4 (24) | 1 | 3 | ||
| Peripheral neuropathy | 4 (24) | 3 | 1 | ||
| ALT elevation | 3 (18) | 2 | 1 | ||
| Epistaxis | 3 (18) | 3 |