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. 2018 Mar 7;7(6):e006462. doi: 10.1161/JAHA.117.006462

Figure 2.

Figure 2

Effects of left ventricular (LV) unloading on end‐diastolic parameters. A, LV unloading with an Impella CP (imp) reduced LV end‐diastolic volume (EDV) and end‐diastolic pressure (EDP), resulting in significantly reduced end‐diastolic wall stress in both the infarct and remote myocardium. Sodium nitroprusside (SNP) also reduced LVEDP, resulting in reduced end‐diastolic wall stress. Systolic aortic pressure (sysAoP) decreased in the SNP group but was maintained in the Impella group without statistical difference (P=0.07 for intergroup comparison). B, Representative 3‐dimensional echocardiographic images before and 2 hours after mechanical LV unloading with Impella. White arrows indicate the Impella catheter. *P<0.05.