Table 3.
SNP | CHR | BP | Nearest Gene | Minor Allele | MAF | Imputation Quality (Rsq) | PEAR‐2 Chlorthalidone Response | |
---|---|---|---|---|---|---|---|---|
β | P Value | |||||||
rs201505549 | 9 | 19 743 120 | SLC24A2 | D | 0.0556 | 0.94 | 15.41 | 2.11×10−09 |
rs61824877 | 1 | 200 242 632 | 69 kb 3′ of C1orf98 | A | 0.0606 | 0.98 | 12.74 | 4.82×10−09 |
rs9927344 | 16 | 12 388 109 | SNX29 | T | 0.11819 | 0.99 | 9.61 | 3.86×10−08 |
rs9943291 | 1 | 120 292 290 | HMGCS2 | G | 0.0637 | 0.97 | 12.51 | 4.17×10−08 |
BP indicates base‐pair position: hg19 position; CHR, chromosome; D, deletion; MAF, minor allele frequency; PEAR‐2, Pharmacogenomic Evaluation of Antihypertensive Response‐2; SE, standard error of the beta coefficient; SNP, single‐nucleotide polymorphism; β, regression coefficient for minor allele.