Table 2.
Functional Annotation Clusters of CaCl2‐Induced Genes With an Influence of B‐Cell Deletion
| Annotation Cluster 1 | Enrichment Score: 33.77128000272969 |
|---|---|
| Category | Term |
| GOTERM_BP_FAT | GO:0006955—immune response |
| GOTERM_BP_FAT | GO:0045321—leukocyte activation |
| GOTERM_BP_FAT | GO:0006952—defense response |
| GOTERM_BP_FAT | GO:0002682—regulation of immune system process |
| GOTERM_BP_FAT | GO:0002684—positive regulation of immune system process |
| GOTERM_BP_FAT | GO:0050776—regulation of immune response |
| GOTERM_BP_FAT | GO:0050778—positive regulation of immune response |
| GOTERM_BP_FAT | GO:0002252—immune effector process |
| GOTERM_BP_FAT | GO:0048584—positive regulation of response to stimulus |
| Annotation Cluster 2 | Enrichment Score: 20.427032466893277 |
|---|---|
| Category | Term |
| GOTERM_CC_FAT | GO:0009897—external side of plasma membrane |
| GOTERM_CC_FAT | GO:0098552—side of membrane |
| GOTERM_CC_FAT | GO:0009986—cell surface |
| Annotation Cluster 3 | Enrichment Score: 15.990954240580606 |
|---|---|
| Category | Term |
| GOTERM_BP_FAT | GO:0006952—defense response |
| GOTERM_BP_FAT | GO:0045087—innate immune response |
| GOTERM_BP_FAT | GO:0050776—regulation of immune response |
| GOTERM_BP_FAT | GO:0050778—positive regulation of immune response |
| GOTERM_BP_FAT | GO:0006954—inflammatory response |
| GOTERM_BP_FAT | GO:0031349—positive regulation of defense response |
| GOTERM_BP_FAT | GO:0031347—regulation of defense response |
| GOTERM_BP_FAT | GO:0045089—positive regulation of innate immune response |
| GOTERM_BP_FAT | GO:0045088—regulation of innate immune response |
| GOTERM_BP_FAT | GO:0002757—immune response‐activating signal transduction |
Functional annotation clusters are shown for genes with induction by CaCl2 treatment in wild‐type mice that were suppressed in muMT mice. GO term: gene ontology term provided in DAVID (the Database for Annotation, Visualization, and Integrated Discovery) analysis. Only the first 10 terms are shown for simplicity.