Table 3.

Prognostic Outcomes as a Function of hsTnI ≥99th Percentile in All Participants and in Those With Presence of Obstructive CAD (Defined as ≥70% Stenosis)

Outcome	HR	95% CI	P Value
Incident MI
All participants (N=991)	2.68	1.86–3.85	<0.001
Obstructive CAD (n=619)	1.87	1.16–3.00	0.01
Nonobstructive CAD (N=226)	8.41	2.77–25.5	<0.001
Incident HF
All participants (N=991)	1.60	1.21–2.13	0.001
Obstructive CAD (n=619)	1.17	0.76–1.80	0.46
Nonobstructive CAD (n=226)	1.61	0.85–3.06	0.14
Cardiovascular death
All participants (N=991)	2.29	1.40–3.75	0.001
Obstructive CAD (n=619)	2.74	1.48–5.06	0.001
Nonobstructive CAD (n=226)	3.60	1.15–11.3	0.03
All‐cause death
All participants (N=991)	1.84	1.22–2.78	0.004
Obstructive CAD (n=619)	2.06	1.26–3.37	0.004
Nonobstructive CAD (n=226)	2.25	0.83–6.12	0.11
Incident MI/HF/all‐cause death
All participants (N=991)	1.62	1.26–2.08	<0.001
Obstructive CAD (n=619)	1.71	1.25–2.33	<0.001
Nonobstructive CAD (n=226)	1.60	0.88–2.90	0.12
Incident MI/cardiovascular death
All participants (N=991)	2.22	1.60–3.08	<0.001
Obstructive CAD (n=619)	2.06	1.40–3.05	<0.001
Nonobstructive CAD (n=226)	4.70	2.17–10.18	<0.001
Incident MI/all‐cause death
All participants (N=991)	2.13	1.56–2.90	<0.001
Obstructive CAD (n=619)	2.06	1.42–2.98	<0.001
Nonobstructive CAD (n=226)	3.62	1.78–7.37	<0.001

CAD indicates coronary artery disease; CI, confidence interval; HF, heart failure; HR, hazard ratio; hsTnI, high‐sensitivity troponin I; MI, myocardial infarction.