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. 2018 Mar 10;7(6):e008105. doi: 10.1161/JAHA.117.008105

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© 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Reappearance of hepatic CETP protein and hepatic macrophage subsets after liposomal clodronate injection. Female APOE*3‐Leiden.CETP mice fed a Western‐type diet were intraperitoneally injected with liposomal clodronate (Lip Clo) and euthanized 3 days (0), 3, 6, and, 9 weeks after injection. Untreated mice were taken along as control (Con). Representative pictures of immunohistochemistry staining of CETP, F4/80, Clec4f, Vsig4 and Ly6C in liver sections from each group are shown. CETP indicates cholesteryl ester transfer protein; Clec4f, C‐type lectin domain family 4; Lip Clo, liposomal clodronate; Ly6C, lymphocyte antigen 6 complex locus C; Vsig4, V‐set and immunoglobulin domain containing 4.