Table 1.
Baseline Characteristics and Outcomes in the 5 Age Groups for the Full Clinical Cohort
| Age: 30 to 39 (N=2664) | Age: 40 to 49 (N=6703) | Age: 50 to 59 (N=6047) | Age: 60 to 69 (N=3112) | Age 70 to 79 (N=1025) | P Value | |
|---|---|---|---|---|---|---|
| Age, y | 35.7±2.81 | 44.7±2.82 | 54.0±2.93 | 63.9±2.84 | 73.0±2.65 | <0.0001 |
| Female | 810 (30.4)1 | 2170 (32.4)1 | 2097 (34.7)2 | 2171 (40.8)3 | 408 (39.8)3 | <0.0001 |
| BMI, kg/m2 | 29.2±6.33 | 28.8±5.12 | 28.8±5.12 | 28.4±4.72 | 27.2±4.01 | <0.0001 |
| Hypertension | 285 (10.7)1 | 1000 (14.9)2 | 1492 (24.7)3 | 1059 (34.0)4 | 444 (43.3)5 | <0.0001 |
| Diabetes mellitus | 83 (3.1)1 | 273 (4.1)1 | 382 (6.3)2 | 248 (8.0)3 | 95 (9.3)3 | <0.0001 |
| Current smoker | 416 (16.2)4 | 892 (13.7)3 | 633 (10.8)2 | 196 (6.6)1 | 53 (5.3)1 | <0.0001 |
| Obesity | 1046 (39.3)4 | 2410 (36.0)2,3 | 2259 (37.4)3,4 | 1072 (34.4)2 | 255 (24.9)1 | <0.0001 |
| Poor CRF | 866 (32.5)4 | 1532 (21.4)1,2 | 1245 (20.6)1 | 724 (23.3)2,3 | 278 (27.1)3 | <0.0001 |
| Deaths | 40 (1.5)1 | 158 (2.4)1 | 287 (4.8)2 | 437 (14.0)3 | 350 (34.2)4 | <0.0001 |
| Cardiovascular death | 11 (0.4)1 | 50 (0.8)1 | 69 (1.1)1 | 133 (4.3)2 | 142 (13.8)3 | <0.0001 |
| Non‐cardiovascular death | 29 (1.1)1 | 108 (1.6)1 | 218 (3.6)2 | 304 (9.8)3 | 208 (20.3)4 | <0.0001 |
Continuous data are presented as mean±SD; categorical data as N (percentage of sample). Poor cardiorespiratory fitness (CRF) defined as functional aerobic capacity (FAC) <80% predicted for age and sex on exercise test. Different superscripts indicate a statistically significant difference between age groups. Superscript 1 is arbitrarily set at the lowest value for each variable. BMI indicates body mass index.