Table 2.
Exercise Test Results for the Full Clinical Cohort
| Age: 30 to 39 (N=2664) | Age: 40 to 49 (N=6703) | Age: 50 to 59 (N=6047) | Age: 60 to 69 (N=3112) | Age 70 to 79 (N=1025) | P Value | |
|---|---|---|---|---|---|---|
| FAC, % | 88.4±19.31 | 94.9±20.22 | 97.1±21.13 | 96.9±23.53 | 93.8±24.72 | <0.0001 |
| Resting HR, bpm | 78.7±13.25 | 77.1±12.84 | 76.4±12.73 | 75.5±12.92 | 74.0±12.41 | <0.0001 |
| Peak exercise HR, bpm | 176.6±15.35 | 170.8±15.74 | 162.9±16.03 | 152.7±17.32 | 142.7±17.31 | <0.0001 |
| Percent pred. peak HR | 96.3±8.31 | 97.6±8.82,3 | 98.0±9.53 | 97.1±10.92 | 95.9±11.51 | <0.0001 |
| HR‐lowering drug use | 142 (5.3)1 | 436 (6.5)1 | 563 (9.3)2 | 424 (13.6)3 | 196 (19.2)4 | <0.0001 |
| Peak HR <85% pred. | 241 (9.1)1 | 568 (8.5)1 | 583 (9.6)1 | 415 (13.3)2 | 169 (16.5)3 | <0.0001 |
| HR recovery | 21.2±8.15 | 20.5±8.04 | 18.9±7.93 | 16.0±7.52 | 12.9±7.41 | <0.0001 |
| HR recovery <13 bpm | 340 (12.8)1 | 993 (14.8)1 | 1279 (21.2)2 | 1022 (32.8)3 | 512 (50.0)4 | <0.0001 |
| Resting SBP, mm Hg | 118.8±14.91 | 120.0±15.62 | 124.0±17.33 | 129.5±18.74 | 133.2±20.35 | <0.0001 |
| Resting DBP, mm Hg | 79.7±11.02 | 79.7±11.12 | 80.5±10.83 | 79.9±10.92,3 | 77.9±11.31 | <0.0001 |
| Peak SBP, mm Hg | 171.0±23.61 | 174.1±23.62 | 179.4±24.63 | 182.3±25.24 | 177.4±20.23 | <0.0001 |
| Peak DBP, mm Hg | 72.9±16.81 | 74.9±15.82 | 77.4±15.53 | 78.7±15.14 | 77.2±14.83,4 | <0.0001 |
| Highest RPE | 18.3±0.84 | 18.3±0.83,4 | 18.2±0.83 | 18.0±0.92 | 17.9±1.01 | <0.0001 |
| Positive exercise ECG | 17 (0.6)1 | 150 (2.2)2 | 266 (4.4)3 | 217 (7.0)4 | 95 (9.3)5 | <0.0001 |
| Abnormal exercise ECG | 62 (2.3)1 | 300 (4.5)2 | 474 (7.8)3 | 356 (11.4)4 | 146 (14.2)5 | <0.0001 |
Continuous data are presented as mean±SD; categorical data as number (percentage of sample). Functional aerobic capacity (FAC) defined as 100%×actual time/predicted time on Bruce protocol for age and sex. Rating of perceived exertion measured on standard Borg Scale (6–20). Positive exercise ECG defined by standard methods. Abnormal exercise ECG defined as positive or abnormal but not diagnostic due to resting ST‐T abnormalities. Different superscripts indicate a statistically significant difference between age groups. Superscript 1 is arbitrarily set at the lowest value for each variable. DBP indicates diastolic blood pressure; HR, heart rate; RPE, rating of perceived exertion; and SBP, systolic blood pressure.