Figure 1.

Average NT‐proBNP (N‐terminal pro‐B‐type natriuretic peptide) evolution in patients with and without the primary end point. NT‐proBNP measurements after the event were deleted, therefore a total of 2009 measurements that occurred before the primary end point were used in this analysis. A, time point zero is denoted as the date of study inclusion (and first NT‐proBNP measurement). B, time point zero is denoted as the moment at which patients either experienced an event, or when they were censored because of reaching the end of the follow‐up duration without experiencing an event. We displayed all repeated NT‐proBNP measurements as years before this moment (ie, on a negative timescale).