Table 1.
Analysis of the associations between eIF3e expression and clinical/pathologic features
| Clinicopathologic features | eIF3e expression | P value | ||
|---|---|---|---|---|
| Low | High | |||
| Total | 241 | 23(10) | 218(90) | |
| Age | ||||
| ≤60years | 128 | 13(10) | 115(90) | 0.730 |
| >60years | 118 | 10(9) | 103(91) | |
| Sex | ||||
| Male | 199 | 16(8) | 180(92) | 0.215 |
| Female | 47 | 7(16) | 38(84) | |
| Tumor size (cm) | ||||
| ≤3 | 148 | 13(9) | 132(91) | 0.707 |
| >3 | 98 | 10(10) | 86(90) | |
| Tumor depth | ||||
| T1 | 27 | 6(22) | 21(78) | 0.032 |
| T2 | 51 | 6(12) | 44(88) | |
| T3+4a | 166 | 11(7) | 153(93) | |
| Lymph node metastasis | ||||
| 0 | 150 | 19(13) | 127(87) | 0.023 |
| ≥1 | 53 | 4(4) | 91(96) | |
| TNM stage | ||||
| ⅠA+ⅠB | 26 | 7(27) | 19(73) | 0.002 |
| ⅡA+ⅡB | 136 | 13(10) | 119(90) | |
| ⅢA+ⅢB+ⅢC | 84 | 3(4) | 80(97) | |
| Histological grade | ||||
| Ⅰ | 5 | 1(20) | 4(80) | 0.620 |
| Ⅱ | 130 | 13(10) | 113(90) | |
| Ⅲ | 65 | 9(8) | 101(92) | |
a Bold values indicate statistical significance (p < 0.05).
Abbreviation: ESCC: Esophageal squamous cell carcinoma; eIF3e: Eukaryotic translation initiation factors 3e.