Table 2.
The difference in median values between benign ovarian masses and early-or advanced-stage EOC according to laboratory variables
Benign ovarian mass, median (IQR) (n=261) | EOC, median (IQR) | P value | ||
---|---|---|---|---|
Stage I-II (n=110) | Stage III-IV (n=119) | |||
Age (years) | 35.0 (21.0)a | 51.0 (14.0)b | 57.0 (15.5)c | <0.001 |
WBC (per µL) | 6220.0 (2350.0)a | 6215.0 (2600.0)a | 6840.0 (3090.0)b | <0.001 |
Hemoglobin (g/dL) | 13.0 (1.4)a | 12.6 (1.5)b | 12.3 (2.0)b | <0.001 |
Platelets (×103/µL) | 253.0 (75.0)a | 271.5 (95.0)a | 328.0 (152.5)b | <0.001 |
CA125 (unit/mL) | 19.0 (21.0)a | 52.7 (227.9)b | 471.6 (751.2)c | <0.001 |
NLR | 1.9 (1.1)a | 2.4 (1.7)b | 3.5 (3.0)c | <0.001 |
PLR | 136.1 (64.2)a | 163.4 (93.1)b | 234.3 (195.0)c | <0.001 |
LMR | 5.4 (2.9)a | 4.8 (3.1)b | 3.2 (2.6)c | <0.001 |
Medians with the same letter (superscript) are not significantly different. P-values for comparisons of medians were obtained using the Kruskal-Wallis test. A post-hoc test (Bonferroni) was applied with pairwise comparison between medians.
EOC, epithelial ovarian cancer; IQR, interquartile range; WBC, white blood cell; CA125, cancer antigen 125; NLR, neutrophil-lymphocyte ratio; PLR, platelet-lymphocyte ratio; LMR, lymphocyte-monocyte ratio