Table 1.
Cardiovascular risk profile of severe dyslipidemia and control group
| Control group (n = 8.538) | Severe dyslipidemia (n = 11.265) | p value | |
|---|---|---|---|
| Average ± SD (95% CI) | Average ± SD (95% CI) | ||
| Age (years) | 50.7 ± 6.04 (50.57–50.83) | 53.51 ± 6.21 (53.4–53.63) | < 0.001 |
| Waist circumference (cm) | 90.64 ± 13.11 (90.36–90.92) | 94.68 ± 13.02 (94.44–94.92) | < 0.001 |
| BMI (kg/m2) | 27.08 ± 5.43 (26.96–27.19) | 29.11 ± 5.01 (29.02–29.2) | < 0.001 |
| SBP (mmHg) | 130.58 ± 15.43 (130.26–130.91) | 136.36 ± 17.21 (136.04–136.68) | < 0.001 |
| DBP (mmHg) | 81.19 ± 9.12 (80.99–81.38) | 84.19 ± 9.78 (84.01–84.37) | < 0.001 |
| Heart rate (beats/min) | 71.52 ± 8.7 (71.33–71.7) | 72.59 ± 8.68 (72.43–72.75) | < 0.001 |
| Glucose (mmol/l) | 5.34 ± 1.07 (5.32–5.37) | 5.74 ± 1.57 (5.71–5.77) | < 0.001 |
| TC (mmol/l) | 4.41 ± 0.44 (4.4–4.42) | 8.08 ± 0.99 (8.06–8.09) | < 0.001 |
| LDL-C (mmol/l) | 2.42 ± 0.43 (2.41–2.43) | 5.35 ± 1.19 (5.33–5.37) | < 0.001 |
| HDL-C (mmol/l) | 1.58 ± 0.36 (1.57–1.59) | 1.6 ± 0.51 (1.59–1.61) | 0.005 |
| TG (mmol/l) | 0.93 ± 0.31 (0.93–0.94) | 2.65 ± 2.27 (2.61–2.7) | < 0.001 |
| SCORE index (points) | 1.22 ± 1.19 (1.2–1.25) | 2.79 ± 2.26 (2.75–2.83) | < 0.001 |
| Arterial Hypertension (%) | 44.2 (43.1–45.3) | 63.5 (62.6–64.4) | < 0.001 |
| Diabetes mellitus (%) | 8.1 (7.5–8.7) | 16 (15.3–16.7) | < 0.001 |
| Abdominal obesity (%) | 30.3 (29.3–31.3) | 51 (50.1–51.9) | < 0.001 |
| BMI > 30 (kg/m2) (%) | 24.1 (23.2–25) | 38.8 (37.9–39.7) | < 0.001 |
| Smoking (%) | 26.4 (25.5–27.4) | 22.7 (21.9–23.5) | < 0.001 |
| Metabolic syndrome (%) | 9.2 (8.6–9.9) | 47.2 (46.3–48.1) | < 0.001 |
| RF ≥ 3 (%) | 44.1 (43.1–45.2) | 84.5 (83.8–85.1) | < 0.001 |
| Family history of CVD (%) | 22.7 (21.8–23.6) | 29.7 (28.9–30.6) | < 0.001 |
| Diet (unbalanced) (%) | 53.5 (52.4–54.5) | 66.5 (65.6–67.4) | < 0.001 |
| Physical activity (insufficient) (%) | 44.2 (43.2–45.3) | 56 (55.1–56.9) | < 0.001 |
Abbreviations: BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, TC total cholesterol, LDL–C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, TG triglycerides, BMI body mass index, RF risk factors, CVD cardiovascular disease, SCORE index Systematic Coronary Risk Evaluation index