Figure 5.

S7 knockdown rescues the effect of BCCIPβ depletion on p53 signaling and cell growth. (A) Control and BCCIPβ kd cells were transfected with control siRNA or S7 siRNA for 48 h, and target proteins were detected by western blotting. (B) Control and BCCIPβ kd cells were transfected with control siRNA or S7 siRNA for 48 h, and mRNA levels of target genes were determined by real-time PCR. (C) Control and BCCIPβ kd cells were transfected with control siRNA or S7 siRNA, and cell growth after 3 days was examined by CCK-8. The results are representative of three different experiments. *P < 0.05; **P < 0.01.