Table 1.
Baseline Characteristics of the Study Cohort
| Characteristic | CM (n = 162) | SMA (n = 138) | CC (n = 133) | CM vs CC (P) | SMA vs CC (P) |
|---|---|---|---|---|---|
| Age (median [25%, 75%]) | 3.9 (2.7, 6.0) | 2.8 (2.1, 4.6) | 4.0 (3.0, 5.7) | .43a | <.001a |
| Sex (n [%] female) | 57 (35.2) | 55 (39.9) | 64 (48.1) | .03b | .17b |
| Height-for-age z score (median [25%, 75%]) | −0.35 (−1.25, 0.53) | −0.90 (−1.7, −0.24) | −0.89 (−1.8, −0.17) | <.001a | .61a |
| Weight-for-age z score (median [25%, 75%]) | −1.2 (−1.9, −0.40) | −1.6 (−2.5, −0.63) | −0.64 (−1.3, 0.10) | <.001a | <.001a |
| Total SES (median [25%, 75%]) | 9.0 (8.0, 10.0) | 8.5 (7.0, 11.0) | 9.0 (7.0, 11.0) | .85a | .88a |
| HIV infection (n [% positive]) | 4 (2.5) | 4 (2.9) | 1 (0.8) | .25b | .19b |
| Mother is primary caregiver (n [%]) | 110 (67.9) | 106 (76.8) | 81 (60.1) | .21b | .005b |
| Maternal education level (n [%] secondary education) | 63 (38.9) | 60 (43.5) | 55 (41.3) | .40b | .99b |
| Possesses sickle cell trait (HbAS) (n [%]) | 2 (1.2) | 2 (1.4) | 19 (14.3) | <.001b | <.001b |
Abbreviations: CC, healthy children recruited from the community; CM, cerebral malaria; HIV, human immunodeficiency virus; SES, socioeconomic status; SMA, severe malarial anemia.
aAnalyzed using the Wilcoxon rank-sum test.
bAnalyzed using the Pearson χ2 test.