Table 3.

Logistic Model of Multidrug- and Carbapenem-Resistant Pseudomonas aeruginosa Adjusted for Patient and Isolate Characteristics in Children Aged 1–17 Years, 1999–2012

Isolate Characteristic*	MDR P aeruginosa (N = 77 439)		CR P aeruginosa (N = 77 439)
	aOR (95% CI)	P	aOR (95% CI)	P
Linear trend, 1999–2012	1.031 (1.025–1.036)	<.001	1.037(1.030–1.044)	<.001
Age (reference, 1–5 y)
6–12 y	1.709 (1.628–1.794)	<.001	1.243 (1.171–1.319)	<.001
13–17 y	3.084 (2.945–3.230)	<.001	2.034 (1.925–2.150)	<.001
Patient location (reference, outpatient)
Inpatient	1.442 (1.382–1.503)	<.001	1.908 (1.813–2.009)	<.001
Inpatient, ICU	1.790 (1.687–1.899)	<.001	2.589 (2.418–2.772)	<.001
Long-term care	2.322 (1.817–2.949)	<.001	1.881 (1.364–2.539)	<.001
Unknown	0.932 (0.728–1.178)	.567	1.765 (1.360–2.255)	<.001
Specimen source (reference, blood)
Respiratory tract	1.818 (1.608–2.062)	<.001	1.157 (1.013–1.327)	.035
Skin	0.399 (0.261–0.589)	<.001	0.572 (0.370–0.851)	.008
Urine	0.789 (0.693–0.902)	<.001	0.734 (0.636–0.850)	<.001
Wound	0.593 (0.518–0.681)	<.001	0.661 (0.571–0.767)	<.001
Region (reference, East North Central)
East South Central	0.676 (0.581–0.783)	<.001	0.531 (0.435–0.643)	<.001
Mid-Atlantic	0.973 (0.903–1.048)	.468	1.045 (0.956–1.143)	.332
Mountain	1.107 (1.107–1.204)	.019	0.900 (0.807–1.003)	.059
New England	0.818 (0.727–0.918)	.001	0.985 (0.854–1.133)	.836
Pacific	0.693 (0.641–0.748)	<.001	0.663 (0.603–0.728)	<.001
South Atlantic	0.917 (0.860–0.978)	.009	0.853 (0.787–0.924)	<.001
West North Central	1.830 (1.721–1.947)	<.001	1.454 (1.349–1.568)	<.001
West South Central	1.031 (0.965–1.101)	.370	0.874 (0.805–0.948)	.001

Abbreviations: aOR, adjusted odds ratio; CI, confidence interval; CR, carbapenem resistant; ICU, intensive care unit; MDR, multidrug resistant.

*Sex was not considered, because no significant differences in the distributions of isolates between male and female patients were found.