Table 2.
Infectious Diarrheal Pathogens Detected From Pediatric Stool Specimens Using the FilmArray Gastrointestinal Panela
| Pathogen | All Ages (n [%]) (n = 1089) | According to Age Group (n [%]) | |||
|---|---|---|---|---|---|
| <1 y (n = 114) | 2–4 y (n = 397) | 5–10 y (n = 295) | 11–17 y (n = 283) | ||
| Bacterial pathogens | 290 (26.6) | 25 (21.9) | 127 (32.0)b | 78 (26.4) | 60 (21.2) |
| Aeromonas | 8 (0.7) | 1 (0.9) | 3 (0.8) | 0 (0) | 4 (1.4) |
| Campylobacter | 14 (1.3) | 0 (0) | 7 (1.8) | 4 (1.4) | 3 (1.1) |
| C difficile | 148 (13.6) | 24 (21.1) | 77 (19.4) | 40 (13.6) | 31 (11.0)b |
| Plesiomonas shigelloides | 3 (0.3) | 1 (0.9) | 1 (0.3) | 0 (0) | 1 (0.4) |
| Salmonella | 21 (1.9) | 1 (0.9) | 4 (1.0) | 5 (1.7) | 11 (3.9) |
| Y enterocolitica | 1 (0.1) | 0 (0) | 0 (0) | 0 (0) | 1 (0.4) |
| Vibrio | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| V cholerae | 1 (0.1) | 0 (0) | 0 (0) | 0 (0) | 1 (0.4) |
| Shigella/EIEC | 22 (2.0) | 0 (0) | 13 (3.3) | 9 (3.1) | 0 (0) |
| Diarrheagenic E coli | 144 (13.2) | 9 (7.9) | 65 (16.4)b | 44 (14.9)b | 26 (9.2) |
| EAEC | 30 (2.8) | 1 (0.9) | 14 (3.5) | 10 (3.4) | 5 (1.8) |
| EPEC | 89 (8.2) | 8 (7.0) | 42 (10.6) | 27 (9.2) | 12 (4.2) |
| ETEC | 11 (1.0) | 0 (0) | 4 (1.0) | 3 (1.0) | 4 (1.4) |
| All STEC | 43 (3.9) | 1 (0.9) | 19 (4.8) | 15 (5.1) | 8 (2.8) |
| E coli O157 | 21 (1.9) | 0 (0) | 9 (2.3) | 7 (2.4) | 5 (1.8) |
| Non-O157 | 22 (2.0) | 1 (0.9) | 10 (2.5) | 8 (2.7) | 3 (1.1) |
| Viral pathogens | 286 (26.3) | 42 (36.8) | 152 (38.3) | 61 (20.7)b | 31 (11.0)b |
| Adenovirus F 40/41 | 71 (6.5) | 11 (9.6) | 37 (9.3) | 14 (4.7) | 9 (3.2)b |
| Astrovirus | 25 (2.3) | 4 (3.5) | 14 (3.5) | 6 (2.0) | 1 (0.4)b |
| Norovirus GI/GII | 124 (11.4) | 16 (14.0) | 70 (17.6) | 23 (7.8) | 15 (5.3)b |
| Rotavirus A | 40 (3.7) | 9 (7.9) | 19 (4.8) | 9 (3.1)b | 3 (1.1)b |
| Sapovirus | 64 (5.9) | 8 (7.0) | 37 (9.3) | 14 (4.7) | 5 (1.8)b |
| Protozoal pathogens | 36 (3.3) | 3 (2.6) | 14 (3.5) | 11 (3.7) | 8 (2.8) |
| Cryptosporidium | 9 (0.8) | 0 (0) | 3 (0.8) | 3 (1.0) | 3 (1.1) |
| C cayetanensis | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| E histolytica | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| G lamblia | 28 (2.6) | 3 (2.6) | 12 (3.0) | 8 (2.7) | 5 (1.8) |
| Codetection | 160 (14.7) | 23 (20.2) | 85 (21.4) | 36 (12.2)b | 16 (5.7)b |
| Negative | 537 (49.3) | 66 (57.9) | 139 (35.0)b | 150 (50.8) | 182 (64.3) |
Abbreviations: EAEC, enteroaggregative E coli; EIEC, enteroinvasive E coli; EPEC, enteropathogenic E coli; ETEC, enterotoxigenic E coli; STEC, shigatoxigenic E coli.
aIn each cell are the number of positive specimens (percentage for diarrheal pathogen). Because multiple pathogens were detected in some children, numbers add up to >100%.
bStatistically significant difference in the frequency of detection relative to diarrheal episodes among children <1 year of age (P < .05).