Table 1.
Distribution of ASP Recommendations and Adjusted Odds Ratios of Adherence According to Primary Service, Prescribing Provider Role, and Recommendation Type
| Categorical Predictora | P (for Group) | Adherence |
||
|---|---|---|---|---|
| n (%) | n (%) | OR (95% CI) | ||
| Primary service | .356 | |||
| Critical care | 376 (58.4) | 275 (73.1) | Reference | |
| Surgical subspecialties | 58 (9.0) | 41 (70.7) | 0.57 (.29–1.14) | |
| General medical | 127 (19.7) | 105 (82.7) | 1.10 (.59–2.05) | |
| Hematology/oncology, stem cell transplant | 83 (12.9) | 74 (89.2) | 1.00 (.34–2.92) | |
| Provider role | .009 | |||
| Nurse practitioner | 243 (37.7) | 164 (67.5) | Reference | |
| Resident | 264 (40.1) | 206 (78.0) | 1.87 (1.15–3.02) | |
| Attending or fellow | 28 (4.3) | 24 (85.7) | 2.95 (.94–9.36) | |
| Pharmacist | 108 (16.8) | 100 (92.6) | 4.73 (1.54–14.57) | |
| Recommendation type | .009 | |||
| Consult with ID physician | 115 (17.9) | 76 (66.1) | Reference | |
| Change antimicrobial therapy | 126 (19.6) | 90 (71.4) | 1.21 (.67–2.17) | |
| Monitor drug levels | 45 (7.0) | 33 (73.3) | 1.80 (.80–4.04) | |
| Discontinue antimicrobial | 198 (30.8) | 44 (77.8) | 2.01 (1.16–3.48) | |
| Optimize dose | 105 (16.3) | 90 (85.7) | 2.62 (1.30–5.24) | |
| IV-to-PO conversion | 20 (3.1) | 19 (95.0) | 5.78 (.72–46.22) | |
Abbreviations: ASP, antimicrobial stewardship program; CI, confidence interval; ID, infectious disease; IV, intravenous; OR, odds ratio; PO, per os/oral.
aThe analysis of each of the 3 variables as a predictor was adjusted for the other 2 variables. The summary P value for each group was calculated using a Wald test.