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. Author manuscript; available in PMC: 2018 Sep 5.
Published in final edited form as: Biochemistry. 2017 Aug 21;56(35):4637–4645. doi: 10.1021/acs.biochem.7b00638

Table 3.

Inhibition constants

Inhibitor Sts-1HP Ki (μM)
Orthovanadate 4.61 ± 0.62
β-glycerophosphate NI1
(−) Tetramisole NI
Methyl-dephostatin NI
1-Naphthyl phosphate NI
2-Bromo-4-hydroxyacetophenone NI
PHPS12 1.05 ± 0.15
Sulfanilic acid 480 ± 55
Sulfanilamide NI
SMP2 48.3 ± 5.61
1

NI = No observable inhibition

2

PHPS1: 4-[2-[1,5-dihydro-3-(4-nitrophenyl)-5-oxo-1-phenyl-4H-pyrazol-4-ylidene]hydrazinyl]-benzenesulfonic acid

3

SMP: 1-(4-sulfophenyl)-3-methyl-5-pyrazolone