Table 1. Geometric mean concentration (GMC) of meningococcal serogroup A-, W- and Y-polysaccharide specific IgA (A) and IgG (B) in saliva and serum before (T0), one month (T1) and one year (T2) after adolescent vaccination.

			MenA	MenW	MenY
A	T0	GMC IgA in saliva; ng/ml (95%CI)	42 (37–46)	13.2 (12.0–14.5)	27.5 (25.0–30.2)
		GMC IgA in serum; ng/ml (95%CI)	61 (52–72)	15.6 (13.0–18.8)	31 (25–38)
	T1	GMC IgA in saliva; ng/ml (95%CI	88 (79–99)	27 (24–31)	52 (47–59)
		T1/T0 IgA ratio saliva (95%CI)	2.1 (1.8–2.5)	2.1 (1.8–2.4)	1.9 (1.7–2.2)
		GMC IgA in serum; ng/ml (95%CI	1,427 (1,225–1,662)	877 (736–1,045)	1,985 (1,658–2,376)
		T1/T0 IgA ratio serum (95%CI)	23 (18–28)	58 (46–73)	64 (50–82)
	T2	GMC IgA in saliva; ng/ml (95%CI	33 (29–37)	10.7 (9.4–12.3)	25 (23–28)
		T2/T0 IgA ratio saliva (95%CI)	0.80 (0.71–0.90)	0.81 (0.71–0.93)	0.93 (0.84–1.02)
		T1/T2 IgA ratio saliva (95%CI)	2.7 (2.4–3.0)	2.5 (2.2–3.0)	2.1 (1.8–2.3)
		GMC IgA in serum; ng/ml (95%CI	330 (282–386)	403 (350–464)	797 (662–960)
		T2/T0 IgA ratio serum (95%CI)	5.35 (4.39–6.50)	26.12 (21.35–31.98)	25.80 (20.32–32.78)
		T1/T2 IgA ratio serum (95%CI)	4.3 (3.8–4.9)	2.2 (1.9–2.5)	2.5 (2.2–2.8)
B	T0	GMC IgG in saliva; ng/ml (95%CI)	4.0 (3.0–5.4)	0.2 (0.1–0.2)	0.4 (0.3–0.5)
		GMC IgG in serum; ng/ml (95%CI)	540 (462–624)	119 (97–146)	65 (54–77)
	T1	GMC IgG in saliva; ng/ml (95%CI	38.4 (31.2–47.3)	4.6 (3.8–5.7)	4.8 (3.9–5.8)
		T1/T0 IgG ratio saliva (95%CI)	10 (6.9–13.3)	28 (21–38)	12 (9.5–15.0)
		GMC IgG in serum; ng/ml (95%CI	27,766 (23,575–32,701)	5,051 (4,104–6,217)	6,045 (4,967–7,358)
		T1/T0 IgG ratio serum (95%CI)	51 (43–61)	43 (33–54)	94 (76–115)
	T2	GMC IgG in saliva; ng/ml (95%CI	5.5 (4.1–7.3)	1.9 (1.4–2.4)	1.7 (1.4–2.1)
		T2/T0 IgG ratio saliva (95%CI)	1.35 (0.96–1.91)	11.35 (8.31–15.51)	4.24 (3.46–5.18)
		T1/T2 IgG ratio saliva (95%CI)	7.3 (5.5–9.7)	2.6 (2.0–3.3)	2.1 (1.8–2.3)
		GMC IgG in serum; ng/ml (95%CI	6,659 (5,778–7,673)	3,204 (2,692–3,813)	1,749 (1,417–2,160)
		T2/T0 IgG ratio serum (95%CI)	12.35 (10.89–14.01)	26.96 (21.38–34.01)	27.08 (22.16–33.09)
		T1/T2 IgG ratio serum (95%CI)	4.2 (3.6–4.8)	1.6 (1.3–1.9)	2.5 (2.2–2.8)