Table 3. Comparison of the percentage and concentration of each IgG4 N-glycan between patients with IgG4-related disease with or without hypocomplementemia.
Hypocomplementemia (+) Patients 1–7 (n = 7) Median (range) |
Hypocomplementemia (−) Patients 8–12 (n = 5) Median (range) |
p value | |
---|---|---|---|
G0 (%) | 36.1 (30.7–44.7) | 36.6 (32.8–48.2) | 0.876 |
G0 (pmol/mg) | 7204.8 (5322.8–7817.3) | 5641.9 (4039.6–9210.5) | 0.432 |
G1 (%) | 23.8 (22.5–24.3) | 24.7 (21.6–27.2) | 0.530 |
G1 (pmol/mg) | 4048.8 (3694.5–5036.2) | 3434.9 (2724.5–6065.8) | 0.343 |
G2 (%) | 39.3 (32.2–45.5) | 37.5 (27.7–45.5) | 0.343 |
G2 (pmol/mg) | 6201.3 (5542.9–9337.7) | 4283.0 (3505.8–12763.2) | 0.202 |
G3 (%) | 0.5 (0.0–1.1) | 0.5 (0.0–0.7) | 0.876 |
G3 (pmol/mg) | 74.7 (0.0–251.2) | 64.0 (0.0–102.5) | 0.755 |
F0 (%) | 3.5 (2.0–4.4) | 6.5 (2.8–9.6) | 0.030 |
F0 (pmol/mg) | 626.8 (394.8–4.4) | 784.2 (722.6–1537.1) | 0.030 |
F1 (%) | 96.5 (95.6–98.0) | 93.5 (90.4–97.2) | 0.030 |
F1 (pmol/mg) | 16,583.9 (14,760.6–21,205.5) | 13,592.5 (10,324.5–27,255.3) | 0.106 |
S0 (%) | 61.0 (52.8–64.8) | 63.5 (55.7–69.7) | 0.343 |
S0 (pmol/mg) | 10,824.6 (8952.8–12,251.5) | 9343.9 (7009.4–15,631.6) | 0.268 |
S1 (%) | 23.7 (21.1–26.1) | 22.0 (19.5–27.5) | 0.530 |
S1 (pmol/mg) | 3854.4 (3600.0–5552.0) | 2835.0 (2432.1–7002.6) | 0.343 |
S2 (%) | 15.4 (13.7–21.2) | 14.0 (10.7–19.3) | 0.202 |
S2 (pmol/mg) | 2622.0 (2412.5–4374.0) | 1930.0 (1358.1–5405.3) | 0.106 |