Table 1.
Differences in scores variation expressed as median and interquartile range
| Baseline | Post‐treatment | Relative variation | P‐valuea | P‐valueb | |
|---|---|---|---|---|---|
| TS Item GERD | |||||
| CG | 63.0 (53.8; 71.0) | 38.0 (30.0; 46.0) | −0.4 (−0.5; −0.2) | <.001 | .013 |
| EG | 56.5 (47.3; 64.8) | 27.5 (19.5; 37.8) | −0.5 (−0.7; −0.4) | ||
| HS | |||||
| CG | 25.0 (20.3; 27.0) | 15.0 (12.0; 19.0) | −0.4 (−0.5; −0.2) | <.001 | <.001 |
| EG | 23.5 (20.0; 26.0) | 7.0 (4.0; 12.0) | −0.7 (−0.9; −0.5) | ||
| RS | |||||
| CG | 25.0 (21.3; 27.0) | 15.5 (12.0; 18.0) | −0.4 (−0.5; −0.3) | <.001 | <.001 |
| EG | 25.0 (21.3; 28.0) | 7.5 (4.0; 11.0) | −0.7 (−0.8; −0.5) | ||
CG, control group (PPI + TAP water); EG, experimental group (PPI + ERW); TS, total score; HS, heartburn score; RS, regurgitation score; ERW, electrolysed reduced water; PPI, proton pump inhibitors.
a
Effect of time assessed by Friedman's test.
b
Differences between PPI and PPI + ERW therapy group assessed by Mann‐Whitney U‐test.
Bolded P‐values are significant after FDR correction.