Table 3.

List of putative circulating miRNA interacted pathways in placenta

KEGG ID	Pathway description	Plasma	EV	Depleted
hsa04510	Focal adhesion	5.81E−15	6.35E−13	7.79E−04
hsa04012	ErbB signalling pathway	3.44E−12	1.24E−13	3.49E−03
hsa04520	Adherens junction	1.12E−11	1.37E−13	1.07E−03
hsa04110	Cell cycle	2.05E−11	2.53E−11	2.25E−02
hsa04917	Prolactin signalling pathway	7.10E−11	2.53E−09	2.22E−02
hsa04151	PI3K‐Akt signalling pathway	1.01E−10	2.57E−10	7.82E−04
hsa04144	Endocytosis	4.92E−10	2.41E−09	7.03E−05
hsa04540	Gap junction	3.70E−09	1.34E−05
hsa04350	TGF‐beta signalling pathway	5.50E−09	1.56E−08	1.79E−05
hsa04666	Fc gamma R‐mediated phagocytosis	1.13E−07	1.56E−08	5.99E−04
hsa04071	Sphingolipid signalling pathway	1.49E−06	4.17E−06	1.56E−03
hsa04664	Fc epsilon RI signalling pathway	2.60E−06	2.07E−05
hsa04370	VEGF signalling pathway	1.21E−04	2.13E−05
hsa04010	MAPK signalling pathway	2.27E−04	3.80E−04	6.45E−02
hsa04530	Tight junction	9.45E−04	3.28E−04	3.86E−03
hsa04512	ECM‐receptor interaction	2.84E−03
hsa04068	FoxO signalling pathway	5.16E−08	4.43E−09	1.11E−02
hsa04152	AMPK signalling pathway	2.19E−03	5.64E−06	5.88E−02
hsa04914	Progesterone‐mediated oocyte maturation	6.89E−03	1.37E−03