Table 1. Characteristics of subjects.
| Subjects Characteristics |
All (n = 72) * | Boys (n = 39) † | Girls (n = 33) ‡ | p-values § | Duration ≤ 5.3 years (n = 36) | | | Duration > 5.3 years (n = 36) | p-values ¶ |
|---|---|---|---|---|---|---|---|
| Age | 12.8 [11.5–15.0] |
13.1 [10.9–14.8] |
12.8 [11.7–15.2] |
p = 0.848 | 12.0 [11.2–14.5] |
14.0 [12.4–15.9] |
p = 0.011 |
| Age at onset | 6.9 [4.7–10.3] |
6.8 [4.8–10.8] |
7.2 [4.3–10.1] |
p = 0.861 | 9.3 [7.3–12.1] |
4.9 [2.7–6.4] |
p < 0.001 |
| Duration of disease | 5.3 [2.9–8.6] |
5.4 [3.2–8.6] |
5.3 [2.3–8.8] |
p = 0.888 | 2.9 [1.3–3.9] |
8.6 [7.0–10.2] |
p < 0.001 |
| BMI SD | 0.51 [-0.17–1.29] |
0.27 [-0.53–0.94] |
1.00 [0.30–1.62] |
p = 0.005 | 0.27 [-0.52–1.29] |
0.75 [0.27–1.29] |
p = 0.149 |
|
HbA1c, last value % (mmol/mol) |
7.3 [6.7–7.8] (57 [50–62]) |
7.4 [6.7–7.9] (57 [50–63]) |
7.3 [6.8–7.6] (56 [51–60]) | p = 0.991 | 7.0 [6.5–7.8] (54 [48–62]) |
7.4 [6.9–8.0] (57 [52–64]) | p = 0.131 |
|
HbA1c, 1-year mean % (mmol/mol) |
7.4 [6.9–7.8] (57 [52–62]) |
7.3 [6.9–7.7] 56 [51–61] |
7.4 [7.0–7.9] (58 [53–63]) |
p = 0.462 | 7.2 [6.7–7.6] (56 [49–60]) |
7.5 [7.1–8.0] (58 [54–64]) |
p = 0.023 |
|
HbA1c, 2-year mean % (mmol/mol) |
7.4 [6.9–7.8] (57 [52–62]) |
7.4 [6.9–7.7] 57.0 [52–61] |
7.3 [7.1–7.9] (57 [54–63]) |
p = 0.614 | 7.1 [6.7–7.7] (54 [49–61]) |
7.5 [7.2–7.9] (58 [55–63]) |
p = 0.019 |
|
Insulin administration: Insulin pump Insulin pen |
n = 45 n = 27 |
n = 26 n = 13 |
n = 19 n = 14 |
n = 18 n = 18 |
n = 27 n = 9 |
||
| Insulin–IU/24h | 40.8 [25.7–56.4] |
36.2 [23.8–51.3] |
42.9 [29.4–63.6] |
p = 0.229 | 34.8 [19.4–56.4] |
46.1 [32.4–59.4] |
p = 0.073 |
| Insulin–IU/kg/24h | 0.8 [0.6–1.0] |
0.8 [0.6–1.0] |
0.9 [0.6–1.0] |
p = 0.523 | 0.8 [0.5–1.0] |
0.9 [0.7–1.0] |
p = 0.193 |
Values are expressed as medians [lower quartile–upper quartile]. HbA1c-values are given as % and due to IFCC standard in parenthesis (mmol/mol). Significant p-values at 0.05 level are in bold.
* n = 68 for “HbA1c, 1-year mean” and n = 63 for “HbA1c, 2-year mean”.
† n = 38 for “HbA1c, 1-year mean” and n = 35 for “HbA1c 2-year mean”.
‡ n = 30 for “HbA1c, 1-year mean” and n = 28 for “HbA1c, 2-year mean”.
§ Comparison of characteristics between boys and girls using Mann-Whitney U-test.
| | n = 32 for “HbA1c, 1-year mean” and n = 27 for “HbA1c, 2-year mean”.
¶ Comparison of characteristics between subjects with a disease duration of less than, and more than, 5.3 years using Mann-Whitney U-test.