Fig 5. Relative mRNA expression levels in the MGF in control and trained animals.
Relative mRNA expression of myosin heavy chain slow isoform (Myh7, panel A), SERCA2 (Atp2a2, panel B), parvalbumin (Pvalb, panel C), mitofusin 1 (Mfn1, panel D), mitofusin 2 (Mfn2, panel E), mitochondrial dynamin-like GTPase (Opa1, panel F) in the fast part of the medial gastrocnemius (MGF) after 2, 4 and 8 weeks of endurance training. Data are presented as mean + SD and normalized by the reference gene (Hprt1). One-sided p-value represents the statistical significance of the training period (2, 4 or 8 weeks) with respect to the control group (Dunnett’s post hoc test) (S9 File). The symbols * denote values significantly different: * p < 0.05, ** p < 0.01, *** p < 0.001.