Table 3.
Adjusted relative risks for new or additional carotid plaque per one standard deviation increase in hepatocyte growth factor, Multi-Ethnic Study of Atherosclerosis, 2000–2012.
| Statistical modela | N with new or additional carotid plaque/total N in model | Relative risk (95% confidence interval) | p value |
|---|---|---|---|
| All participants | |||
| Model 1 | 1900/3400 | 1.07 (1.04, 1.09) | <0.0001 |
| Model 2 | 1.04 (1.01, 1.08) | 0.005 | |
| Non-Hispanic white Americans | |||
| Model 1 | 794/1335 | 1.05 (1.02, 1.09) | 0.003 |
| Model 2 | 1.04 (0.99, 1.09) | 0.1 | |
| Chinese Americans | |||
| Model 1 | 219/438 | 1.03 (0.93, 1.13) | 0.6 |
| Model 2 | 1.03 (0.92, 1.14) | 0.6 | |
| African Americans | |||
| Model 1 | 485/893 | 1.05 (0.98, 1.12) | 0.1 |
| Model 2 | 1.02 (0.95, 1.09) | 0.6 | |
| Hispanic Americans | |||
| Model 1 | 402/734 | 1.09 (1.05, 1.13) | <0.0001 |
| Model 2 | 1.09 (1.04, 1.15) | 0.001 | |
a
Relative risk regression with outcome new or additional carotid plaque and predictor one standard deviation (259 pg/ml) increase of hepatocyte growth factor.
Model 1 - Adjusted for age, race/ethnicity, and sex.
Model 2 - Adjusted for Model 1 plus baseline values of body mass index, smoking status, diabetes mellitus, systolic blood pressure, antihypertensive medication use, high-density lipoprotein cholesterol, total cholesterol, lipid medication use, time elapsed between visits 1 and 5, level of education, and physical activity.