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. 2018 Mar 30;9(24):16678–16690. doi: 10.18632/oncotarget.24659

Figure 2. Chemerin increases endothelial cell adhesion molecules mRNA expression in HMEC-1 cells.

Figure 2

Serum starved HMEC-1 cells were treated with chemerin (0-10nM) for 4 hours. Real-time quantitative RT-PCR analyses showed that mRNA expression of cell adhesion molecules, i.e. E-selectin, VCAM-1 and ICAM-1, were significantly up-regulated by chemerin in a concentration dependent manner at 4 hours (Figures 2A-2C: ***P < 0.001 vs. basal). Data are mean ± SE of three experiments. Each experiment was carried out in three replicates. Group comparison by ANOVA (post hoc analysis: Tukey's test).