Table 3. Biomarkers of venous thromboembolism.

Variable	VTE-positive	VTE-negative	P-value
CRP (mg/dL)	0.42 (0.04–6.64)	0.21 (0.02–10.21)	0.13
D-dimer (ng/mL)	3.9 (0.6–23.6)	0.9 (0.1–8.8)	<0.0001
FDP (μg/mL)	10.6 (2.9–55.7)	6.4 (2.0–45.6)	0.004
Fibrinogen (mg/dL)	254 (238–589)	340 (202–589)	0.15
TAT III (ng/mL)	7.9 (2.6–60.0)	2.9 (1.3–31.5)	<0.0001
Total PAI-1 (ng/mL)	20.0 (10.0–54.0)	18.0 (4.0–64.0)	0.14
F1 + 2 (pmol/L)	264 (248–1,050)	211 (63–995)	<0.0001
Factor 2 (%)	86 (66–114)	87 (0–122)	0.72
Factor 7 (%)	82 (57–108)	82 (36–142)	0.24
Factor 8 (%)	117 (64–200)	111 (49–200)	0.95
Factor 10 (%)	84 (58–121)	84 (31–121)	0.64
VEGF (pg/mL)	34.0 (20.0–103.0)	24.5 (18.0–236.0)	0.15
IL-10 (pg/mL)	0.41 (0.18–1.46)	0.36 (0.13–4.24)	0.32
IL-1b (pg/mL)	0.05 (0.02–0.29)	0.06 (0.00–0.38)	0.72
IL-6 (pg/mL)	3.08 (0.65–9.71)	1.37 (0.19–13.40)	0.01
IL-8 (pg/mL)	35.20 (11.10–85.50)	20.00 (6.80–336.00)	0.008
GM-CSF (pg/mL)	0.20 (0.05–5.98)	0.10 (0.00–4.90)	0.01
TNF-β	0.30 (0.13–0.65)	0.30 (0.02–0.62)	0.92
CCL2	254.0 (164.0–639.0)	252.0 (144.0–531.0)	0.66
CCL22	1,110.0 (727.0–2,070.0)	970.0 (308.0–8,020.0)	0.12
CCL3	15.5 (6.1–30.6)	15.6 (4.7–42.5)	0.99
CCL4	135.0 (45.0–339.0)	119.0 (42.0–661.0)	0.56

Abbreviations: CCL, C-C motif ligand; CRP, C-reactive protein; GM-CSF, granulocyte macrophage colony-stimulating factor; IL, interleukin; PAI-1, plasminogen activator inhibitor-1; TNF-β, tumor necrosis factor-beta; VEGF, vascular endothelial cell growth factor.