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. 2018 Mar 30;9(24):16962–16973. doi: 10.18632/oncotarget.24764

Table 2. Summary of biological activities of the compounds (1)–(6) in human prostate cancer cells.

Actitiy* Compound
(1) (2) (3) (4) (5) (6)
Cytotoxicity ++ +++ + +++ + ++
Anti-proliferative activity + ++ + ++ + +
Pro-apoptotic activity ++ +++ + +++ + ++
Autophagy inhibition ++ ++ +++ +++ + +
AR signaling inhibition +++ +++ - ++

*“+++” – high activity; “++” – moderate activity; “+” – low activity; “–” – no activity.