Table 1. Clinical characteristics of the TRIMEL-loaded DCs treated melanoma patients.
Patient code | Gender | AJCC stage | Primary tumor localization | Metastasis | Additional treatment | DTH response | Overall survival (months) |
---|---|---|---|---|---|---|---|
MT061p | M | IV | Urethral meatus | M1c | CTX | – | 10.8† |
MT065p | F | IV | Scalp | M1c | CTX | – | 5.7† |
MT066p | M | IIIC | Abdominal wall | ND | DTIC, RT | + | 47.7† |
MT072p | M | IV | Dorsal | M1c | NA | – | 15.2† |
MT076p | F | IV | Left foot | M1b | RT | + | 35.1† |
MT079p,g | F | IV | Left flank | M1c | Surgery | – | 9† |
MT080p,g | M | IV | Palate | M1c | Surgery, RT | + | 68.3 |
MT083g | M | IIIC | Right hand | N4 | Surgery | – | 17† |
MT084g | M | IIIC | Right foot | N4 | Surgery | + | 65.3† |
MT087g | M | IV | Right hand | M1b | Surgery, RT | NT | 1.4† |
MT089g | M | IV | Right foot | M1b | Surgery, RT | NT | 6.2† |
MT091p,g | M | IV | Scalp | M1c | Surgery, RT | + | 50.6† |
MT093g | F | IV | Uveal melanoma | M1c | Surgery | + | 64.9 |
MT094g | M | IV | Head/Neck | M1c | Surgery | NT | 3.4† |
MT096g | M | IIIA | Dorsal | N2a | Surgery | + | 31† |
MT098g | M | IV | Right hand | M1c | Surgery | NT | 2.6† |
MT101g | M | IV | Dorsal/Right leg | M1a | Surgery | – | 63.9 |
MT105p | F | IIIA | Right leg | N2a | NA | – | 63.5 |
MT109p | F | IV | ND | M1c | Surgery | NT | 2.4† |
MT114p | M | IV | Thoracic wall | M1c | RT, IFN-α | – | 10.7† |
MT122p | M | IIIC | Left leg | ND | NA | + | 29.9† |
MT123p | M | IV | Left flank | M1c | RT | – | 6.9† |
MT127p | F | IV | Left foot | M1b | NA | + | 12.1† |
MT128p | F | IIIB | Right shoulder | N2c | RT | + | 56.5 |
MT132p | M | IV | Uveal melanoma | M1c | DTIC | – | 43.6† |
MT141p | M | IV | Knee | M1c | RT | – | 20.5† |
MT147p | F | IV | Left leg | M1b | RT | + | 12.8† |
MT158p | M | IV | Right shoulder | M1a | Surgery, RT | + | 10.2† |
Abbreviations: p, protein expression analysis; g, gen expression analysis; F, Female; M, Male; AJCC, American Joint Committee on Cancer; ND, Not determined; RT, Radiotherapy; CTX, Chemotherapy; DTIC, Dacarbazine; NA, Not apply; NT, Not tested; †, Deceased.