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. 2018 Mar 30;9(24):17117–17132. doi: 10.18632/oncotarget.24965

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Copyright: © 2018 Chekol et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

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(A–C) Radioligand binding assay and immunoreactive fraction determination of ⁸⁹Zr-DFO-nimotuzumab in EGFR-positive DLD-1 cells. (A) Radioligand binding assay ⁸⁹Zr-DFO-nimotuzumab showed a K_D of 14 ± 2.4 nM with a ~ 577,000 EGFR/cell. (B & C) The immunoreactive fraction of ⁸⁹Zr-DFO-nimotuzumab was 0.73.