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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Fam Cancer. 2018 Apr;17(2):225–228. doi: 10.1007/s10689-017-0031-9

Figure 1.

Figure 1

H&E section of the colonic carcinoma showing that the tumor is poorly differentiated with a solid growth pattern (A). By immunohistochemistry, the tumor cells are positive for cytokeratin CAM5.2 (B); they show loss of staining for MLH1 (C), PMS2 (D), MSH2 (E), and MSH6 (F) with appropriate positive internal control for each of the 4 stains (all figures at 200× magnification; scale bar, 500 μm).