Fig. 5.

A schematic representation of the CircAdapt model together with the TriSeg and the MultiPatch models as its extensions is given in the orange box. Known physiological adaptation rules are used to adapt geometry parameters with the aim to match clinical measurements for mean systemic pressure and flow given in input to the model. The model gives in output hemodynamic and anatomical response in the form of geometry parameters as a consequence of adaptation, and pressure-volume relationships. When extended to the MultiPatch model, local electrical activation is needed as an additional input to provide information about stress, strain, and work within ventricular walls