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. 2018 Apr 19;8:6264. doi: 10.1038/s41598-018-24657-9

Figure 5.

Figure 5

FC-map of the hippocampus. Statistical zFC-maps of the right hippocampus are shown for 3 and 7 months old APPNL/NL and APPNL-F/NL-F mice. Five slices of the zFC-maps are shown an anatomical T2-weighted MRI image and overlaid with the Franklin and Paxinos anatomical mouse brain atlas29 with indication of the stereotactic coordinates a = interaural, b = bregma. Color scale represents the T-value (one-sample T-test), i.e. strength of FC of the right hippocampus with all other voxels in the brain. Graphs show strength of FC as z-scores for FC of the hippocampus bilaterally, FC between the hippocampus and frontal cortex and between the hippocampus and retrosplenial cortex. *p < 0.05, **p < 0.01, ***p < 0.001, two-way ANOVA, corrected for multiple comparisons.