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. 2018 Apr 19;8:6281. doi: 10.1038/s41598-018-24462-4

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Heat map of lacunae shared across different acute severe malarial anaemia sera comparisons. P. falciparum antigen lacunae were grouped by recurrence across different comparisons with acute sera from severe malarial anaemia subjects. Each column displays the seroreactivity profile of one serum sample, and each row displays the seroreactivity profile of an individual protein fragment. Grey color indicates no seroreactivity, black is low-to-moderate seroreactivity, and red denotes high seroreactivity to probed fragments. Lacunae present across more than one comparison are designated by a triangle.