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. 2018 Apr 19;8:6250. doi: 10.1038/s41598-018-24727-y

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Functional annotations and enriched canonical pathways of the 25 targeted core DE miRNAs. (A) Functional annotation of all the targets by 25 core DE miRNAs. (B) A relationship network showing the predicted genes corresponding to the 25 core DE miRNAs between lactation and non-lactation, which are highly related to mammary gland development and mammary epithelial cell proliferation. (C) These relationships of these target genes with DE miRNAs. (D) Enriched canonical pathways related to lactation initiation.