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. 2018 Apr 13;9:742. doi: 10.3389/fimmu.2018.00742

Figure 1.

Figure 1

Effect of genetic ablation of Mertk on naive and arthritic knee joints with KRN serum transfer arthritis (STA). (A) Naive (n = 6 mice) or arthritic (KRN STA) wild-type (WT) and Mertk−/− mice (n = 9–15 mice) were euthanized at day 7. Shown are representative pictures of histological knee joint sections stained with safranin O and fast green. (B) Macroscopic score of knee joints of arthritic mice as determined by swelling and blood vessel formation (n = 18–30 knee joints). (C) Histological knee joint sections of arthritic mice were scored for the arthritis parameters depicted. Three semi-serial sections per joint were scored in a random and blinded manner with an arbitrary score from 0 to 3 (n = 10–18 knee joints). P, patella; F, femur; S, synovium. For (B,C), data are represented as mean + SEM. *p < 0.05, **p < 0.01 with unpaired t-test.