Table 4.
Groups | −ve control | Chi | Vit E/Glu | TQ 2.5/Glu | TQ 10/Glu |
---|---|---|---|---|---|
Cyto-c gene expression | 1.032 ± 0.014 | 9.67 ± 0.895* | 2.77 ± 0.148@ | 5.407 ± 0.98@ | 2.40 ± 0.264X,@ |
Glu was injected i.p. as a single dose for 7 days. TQ and Vit E were injected as a single dose for 7 days. Animals in each group were subjected to the neurobehavioral tests. Once they were scarified, their brains were retrieved and homogenized in its suitable buffer and used in RT-PCR assay.
Statistical analysis of mean Cyto-c gene expression (RQ) were performed using one-way analysis of variance (ANOVA) followed by Tukey’s multiple comparison tests, by graph pad prism 5. Each value represents the mean value of 12 rats ± SEM.
*Statistically significant from −ve control group (p < 0.05).
@Statistically significant from Glu group (p < 0.05).
XStatistically significant from TQ 2.5/Glu group (p < 0.05).