Table 5.
Group | −ve control | Glu | Vit E/Glu | TQ 2.5/Glu | TQ 10/Glu |
---|---|---|---|---|---|
Concentration of Caspase-3 (ng/ml) | 7.833 ± 1.218 | 37.43 ± 2.260* | 18.15 ± 0.7610@ | 13.95 ± 0.4288@ | 5.550 ± 0.2742@,#,X |
Glu was injected i.p. as a single dose for 7 days. TQ and Vit E were injected as a single dose for 7 days. Animals in each group were subjected to the neurobehavioral tests before being sacrificed. The brains were isolated and homogenized as 10% homogenate in 0.1 M PBS then centrifuged, and supernatants were used in the Casp-3 ELISA kit. Statistical analyses of mean Casp-3 level were performed using ANOVA followed by Tukey’s multiple comparison tests, by graph pad prism 5. Each value represent the mean value of 12 rats ± SEM.
*Statistically significant from −ve control group (p < 0.05).
@Statistically significant from Glu group (p < 0.05).
#Statistically significant from Vit E/Glu group (p < 0.05).
XStatistically significant from TQ 2.5/Glu group (p < 0.05).