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. 2018 Apr 19;8:6240. doi: 10.1038/s41598-018-24662-y

Table 7.

Mean fasting plasma glucose and HbA1c in participants with non - diabetic hyperglycemia a or impaired fasting glucose where glycemic category changed (progressed or regressed), or remained unchanged, on a repeat second baseline sample taken a median 40 days latera.

Regressed Unchanged Progressed Overall p
Non diabetic hyperglycemia
n 312 1047 104
Fasting plasma glucose (mmol/L) 5.6 (0.6)*** 5.9 (0.6) 6.1 (0.7)*** 0.0001
HbA1c % (mmol/mol) 42.8 (1.1)*** 43.9 (1.4) 45.4 (1.4)*** 0.0001
HbA1c (%) 6.1 (0.1)*** 6.2 (1.4) 6.3 (1.4)***
Impaired fasting glucose
n 343 494 113
Fasting plasma glucose (mmol/L) 6.3 (0.2)*** 6.4 (0.2) 6.6 (0.2)*** 0.0001
HbA1c % (mmol/mol) 42.0 (3.9)*** 44.2 (4.3) 46.6 (4.4)*** 0.0001
HbA1c (%) 6.10 (0.36)*** 6.2 (4.3) 6.4 (4.4)***

aNon diabetic hyperglycemia (NDH) on first sample defined as HbA1c ≥6% (≥42–<48 mmol/mol) and impaired fasting plasma glucose as ≥6.1 mmol/L–<7.0 mmol/l. The term regression means the second baseline sample was HbA1c <6% (<42 mmol/mol) or fasting plasma glucose <6.1 mmol/L on repeat baseline sample. The term progression means the second baseline sample was HbA1c ≥6.5% (≥48 mmol/mol) or fasting plasma glucose ≥7.0 mmol/L. Median 40 days (interquartile range 27–69 days) between paired baseline data. Please note total sample size (n = 950) for IFG is slightly lower than in Tables 13 as repeat sample not undertaken.

***p < 0.001 compared to unchanged group. Across group comparisons by one-way ANOVA model, and two-way comparison is based on an independent samples test. Data shown as mean (SD).