Table 1.
Primary and secondary outcomes. “X” indicates that this outcome was assessed at the time point indicated in the column above. VS: viral suppression. VL: viral load. CASI: computer-assisted self-interviewing. ART: antiretroviral therapy.
| Outcome | Source | 13 weeks | 26 weeks | 39 weeks | Description | |
| Primary study outcomes |
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VS defined as VL below the lower limit of detection in the 6-week window before the scheduled study visits | Chart review (any value in 6-week window before scheduled visit) OR laboratory value collected at study visit | X | X |
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<40 copies/mL or lower limit of detection for site-specific assay used to test the specimen |
| Secondary study outcomes |
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VL suppression defined as VL below the lower limit of detection in the 6-week window before the scheduled study visits | Chart review (any value in 6-week window before scheduled visit) OR laboratory value collected at study visit |
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X | <40 copies/mL or lower limit of detection for site-specific assay used to test the specimen |
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Engagement in care | CASI survey | X | X | X | Completion of HIV-related care clinic visit in last 3 months |
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ART uptake (for participants not on ART) | CASI survey | X | X | X | “Are you currently taking medication to treat your HIV (Y/N)?” |
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ART adherencea (for participants on ART) | CASI survey | X | X | X | (1) “How many times during the day has your doctor told you to take a dose of medicine (pills or other medicines) to treat your HIV?” and (2) “Thinking about the last 7 days, how many times did you miss taking a dose of pills?”[64] |
aOutcome of >90% adherence is comprised 2 components (1) is the denominator, indicating the frequency of doses prescribed (multiplied x7 to represent total weekly doses); (2) is the numerator, indicating the number of times, total, a dose was missed.