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. 2018 Apr 1;29(4):424–436. doi: 10.1089/hum.2017.179

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Copyright 2018, Mary Ann Liebert, Inc.

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Figure 5. — Combined outer nuclear layer transduction efficiency and inner retinal tropism of seven AAV serotypes in retinal explants. (A) Dot plot showing all individual data points for the mean % GFP-positive cells in the outer nuclear layer produced by each AAV serotype in all three donor eyes combined. (B) Bar graph demonstrating the inner nuclear layer tropism combined for all three donor eyes expressed as the percentage of z-stacks that displayed GFP-positive cells. (C) Bar graph demonstrating the ganglion cell layer and nerve fiber layer (GCL/NFL) tropism combined for all three donor eyes expressed as the percentage of z-stacks that displayed GFP-positive cells. Error bars represent SEM (there are no error bars for AAV4 and AAV6 in the GCL/NFL graph because tropism was 100% in all z-stacks assessed across all three eyes).