TABLE 2 .
Impact of TRP75-interacting protein knockdown on E. chaffeensis survival in host cells
| Parameter | No. (%) of genes whose knockdown had an impact on E. chaffeensis infection |
Total no. of genes | ||
|---|---|---|---|---|
| Inhibition | Promotion | No significant change | ||
| Day | ||||
| 1 | 50 (58) | 0 | 36 (42) | 86 |
| 2 | 63 (73) | 0 | 23 (27) | 86 |
| Overall | 74 (86) | 0 | 12 (14) | 86 |
| Category of primary function | ||||
| Cell signaling | 20 | 0 | 3 | 23 |
| Vesicle trafficking and intracellular transport | 19 | 0 | 2 | 21 |
| Metabolism | 18 | 0 | 2 | 20 |
| Others | 6 | 2 | 8 | |
| Transcriptional regulation | 4 | 0 | 3 | 7 |
| Posttranscriptional modification | 5 | 0 | 0 | 5 |
| Apoptosis | 2 | 0 | 0 | 2 |
| Total | 74 | 0 | 12 | 86 |