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Competitive inhibition of Gal-3 (5.56 μM) binding to ASF using monovalent carboxy-functionalized compound 9 (A) and multivalent TDG-conjugates 11 and 12 at indicated concentration (B). Refer to Scheme 2 and Scheme 3 for compound structures. The subtracted blank value (no Gal-3) was 0.091 ± 0.005.
