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| inhibitor | IC50 (nM)a | number of loaded TDG moieties (−)b | relative inhibitory potency | relative inhibitory potency per glycan |
|---|---|---|---|---|
| 9 | 9030 ± 27 | 1.0 ± 0.0 | 1.0 ± 0.0 | 1.0 ± 0.0 |
| 11 | 19.40 ± 1.09 | 7.0 ± 1.0 | 465.5 ± 27.5 | 66.5 ± 13.4 |
| 12 | 1.88 ± 0.38 | 18.7 ± 1.6 | 4803.2 ± 985.2 | 256.9 ± 74.7 |
ELISA.
TNBSA-assay.
