Figure 4.

Effects of methanol extract of Brassica oleracea var. capitata L. on histopathological changes in contact dermatitis mice. Ear tissues were stained with hematoxylin and eosin and observed using a light microscope. Abbreviations are the same as in Upper left, NOR; upper right, CTL; middle left, 30 μg/ear of MEBO-treated; middle right, 100 μg/ear of MEBO-treated; bottom left, 300 μg/ear of MEBO-treated; bottom right, DEX (X50). Yellow bars indicate epidermal thicknesses, filled arrows mean hyperkeratotic areas (a). The epithelial thickness and immune cell infiltration were evaluated in a quantitative manner. Abbreviations are the same as in Figure 2. All values are presented as the mean ± standard deviation.^##P < 0.01 versus nontreated NOR mice, *P < 0.05 versus nontreated contact dermatitis mice (b)