Fig. 4.

Change over time in the no-flow region (NF) volume after contrast agent injection in reperfused and non-reperfused myocardial infarct. The first NF measurement performed at 2 min after contrast agent injection by early gadolinium enhancement imaging was considered the reference. *Significant reduction in the NF volume compared to the reference was observed at 20 min and thereafter in the reperfused model; ^#significant reduction in the NF volume compared to the reference at 25 min and thereafter in the non-reperfused model