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Changes in parameters over the 24-week study (t-tests)
| Baseline | Week 24 | ||
|---|---|---|---|
|
| |||
| Mean(S.D.) | Mean (S.D.) | P value | |
| SBP (mm Hg) | 160.5(16.4) | 139.6(15.6) | <.0001 |
| DBP(mm Hg) | 88.4 (13.7) | 80.7 (13.2) | 0.008 |
| cSBP (mm Hg) | 167.4(20.8) | 146.6(24.6) | <.0001 |
| HR (bpm) | 77.3 (12.5) | 72.7(12.3) | 0.0112 |
| eGFR (mL/min/1.73 m2) | 72.5 (17.6) | 69.3(17.9) | 0.07 |
| HbA1c (%) | 5.98(1.08) | 6.00 (1.05) | 0.3892 |
| LDLC (mg/dL) | 134.7(22.1) | 121.5(23.8) | 0.008 |
| ATII (pg/mL) | 12.0(6.4) | 27.1(50.6) | 0.159 |
| PAC (pg/mL) | 140.2(46.0) | 100.7 (46.5) | <.0001 |
