Figure 1.

PRDM9 alleles and ZnF arrays in Holstein and Jersey cattle. (a) Allele and ZnF array information in Holstein and Jersey cattle. ZnF arrays were coded from A to J according to the full length amino acid composition, and the three important sites were shown (–1, 3 and 6) that may be same for different ZnF arrays. Alleles were coded from allele 1 to allele 5 based on their ZnF array composition. (b) PRDM9 gene structure and comparison between non-allele 5 and allele 5. Four domains (KRAB, SET, single ZnF, 6 to 7 ZnF repeats) were present in bovine PRDM9. Allele 5 was perfectly linked with the minor allele of the SNP at Chr1: 45112924 (R² = 1). Comparing between non-allele 5 and allele 5, amino acid frequencies at each positions were shown as proportional to the size of the letters (one ZnF includes 28 amino acids). Positions with different amino acid components between allele 5 and other alleles were highlighted by “*”.