Table 1. Methylation status at GAAGA/TCTTC sites in H. pylori deletion strains. SMRT sequencing was performed to determine the loss of m4C methylation in the genome.
| Strain | Number of GAAGA sites | Total GAAGA sites methylated | Number of TCTTC sites | Total TCTTC sites methylated | NCBI accession number |
|---|---|---|---|---|---|
| 26695 ΔR.hpyAII | 4816 | 4816 (100%) | 4816 | 4813 (99.94%) | CP026326 |
| 26695 ΔR.hpyAII-M2.hpyAII | 4818 | 4813 (99.9%) | 4816 | 0 | CP026324 |
| 26695 ΔR.hpyAII-M2.hpyAII:: M2.hpyAII:: gen | 4828 | 4828 (100%) | 4828 | 4826 (99.96%) | CP026515 |
| 26695 ΔR.hpyAII-M1.hpyAII | 4827 | 4826 (99.99%) | 4827 | 4826 (99.99%) | CP026325 |
| 26695 ΔR.hpyAII-M1.hpyAII-M2.hpyAII | 4817 | 4750 (98.61%) | 4817 | 0 | CP026323 |