Table 3. Cox regression modelling of baseline characteristics and attrition comparing baseline CD4 categories > 500 cells/μL and 0–500 cells/μL.
Crude hazard ratio (95% CI) | P | Adjusted hazard ratio (95% CI) | P | ||
---|---|---|---|---|---|
Baseline CD4 | > 500 | 1,24(1,03–1,48) | 0,022 | 1,26(1,05–1,52) | 0,014 |
(cells/μL) | 0–500 | 1 | 1 | ||
gender | Male | 1,06(0,9–1,25) | 0,483 | 1,23(1,03–1,47) | 0,025 |
Femaile | 1 | 1 | |||
Agecategory | 18–25 | 1,29(1,07–1,56) | <0.001 | 1,3(1,07–1,58) | 0,002 |
26–35 | 1 | 1 | |||
36–45 | 0,91(0,73–1,12) | 0,9(0,72–1,11) | |||
46–55 | 0,7(0,5–0,97) | 0,69(0,49–0,96) | |||
>55 | 0,82(0,46–1,46) | 0,8(0,45–1,44) | |||
Pregnant at baseline | Yes | 1,36(1,01–1,82) | 0,045 | 1,27(0,93–1,72) | 0,134 |
clinic | Metro 1 | 1 | 0,279 | 1 | 0,137 |
Metro 2 | 1,05(0,88–1,26) | 1,16(0,95–1,43) | |||
Rural 1 | 0,89(0,71–1,11) | 0,96(0,75–1,23) | |||
Baseline TB | Yes | 0,91(0,51–1,61) | 0,744 | 0,94(0,53–1,68) | 0,841 |
Previous ART of > 3 mths | Yes | 0,88(0,5–1,56) | 0,667 | 0,91(0,51–1,61) | 0,739 |
Year ART start | 2014 | 0,86(0,72–1,02) | 0,088 | 0,81(0,66–1) | 0,051 |
2015 | 1 | 1 |
Proportional hazards assumptions were checked with scaled Schoenfeld residuals. Likelihood ratios were used to estimate P values in regression models where categorical variables had more than two strata. Model fits were assessed as good based on the likelihood ratio test statistic. Selection of baseline variable category for comparison (HR = 1) was based on sample size and clinical significance.